Published Research Summaries (click "Search" in Menu to filter)

Cannabis and Sleep Disorders

Published in February 2022 in the journal Clinical Neuropharmacology, this review article examined research primarily on CBD and THC and their impact on sleep disorders.

Cancer and pain patients show cannabis treatment is effective

This was a prospective study of over 10,000 patients from Israel's largest medical cannabis clinic that identified treatment adherence, safety, and effectiveness of medical cannabis. It was published in Frontiers in Medicine in February 2022.

Parkinson's patients and cannabis (study)

This study examined the self-reported benefits of cannabis used by Parkinson's Disease patients in Norway in 2021. It was published in February 2022 in the journal Acta Neurologica Scandinavia.

Cannabis helps reduce opioid use in patients with chronic back pain

The study compared the average morphine milligram equivalent (MME) doses of patients before initiating cannabis and after initiating medical cannabis. Patients completed pain and disability questionnaires after 3, 6, and 9 months of cannabis use.

Inhaled cannabis is effective for several types of pain

The primary purpose of this study was to determine if inhaled cannabis decreases self-reported joint, muscle, or nerve pain ratings. Spoiler alert: it does. It was published in February 2022 in the journal Cannabis and Cannabinoids Research.

CBD-A + CBD extract inhibits pancreatic cancer cells in model

This is a study that built on previous work identifying CBD as a molecule that induced cancer cell death in vitro (test tube). Their primary goal was to compare different extraction methods' ability to induce "apoptosis", or cancer cell suicide/death in vitro for a human pancreatic cancer model. It was published in the journal Molecules in February 2022.

Medical cannabis helps reduce opioid use in chronic pain patients

Published in the January/February edition of the journal Pain Physician, this study focused on the effects of medical cannabis on opioid dosing in chronic pain patients. It included 115 patients from a Pennsylvania institute for pain medicine.

Cannabis use correlated with decreased mortality in trauma patients

Published in The American Surgeon in February 2022, this study compared outcome data from intensive care unit (ICU) adult trauma patients that tested positive for cannabis use (pMS, or positive marijuana, or THC screen), and those that tested negative for all drugs and alcohol.

CBD has positive impact on children with drug-resistant epilepsy

This study examined the effectiveness, safety and tolerability of CBD used with standard medical anti-seizure treatment in children with drug-resistant epileptic encephalopathies (DEEs). It was published in the European Journal of Epilepsy in January 2022.

Seniors say cannabis helps with pain & sleep

This study looked at 9,766 older adults' use of medical cannabis in Canada from 2014 to 2020 and was published in December 2021 in the journal Drugs & Aging. All participants were at least age 65 and their average age was 73.

THC + CBD Flower lifts mood without the paranoia

This interesting study examined the effects of 3 different types of cannabis flower with ratios of THC%:CBD% of 24:1, 9:10, and 1:23. It was published in the journal Addiction Biology in January 2022.

Skin Health: Study shows CBG has benefits

Published in the journal Molecules in January 2022, this research claims to be the first to specifically study the effects of CBG on human skin. They compared in-vitro effects of CBD and CBG, and then tested CBG on human skin.

Cannabinoids & Breast Cancer Research Update

This is a review study specifically on cannabinoids and their effect on breast cancer published in the journal Molecules in December 2021. The authors state that "cannabinoids are promising therapeutic agents for the different breast cancer subtypes, being able to exert important actions on cell survival and metastasis."

Study: Minor Cannabinoids May Be Ready for the Spotlight

This was a meta-study that focused on about ten "minor" cannabinoids (not THC or CBD) research and their effects. It was published in November 2021 in Frontiers in Pharmacology.

Differences in Cannabinoid Content by Extraction Method

Study: Cannabinoid Extraction Methods Matter

Overall, super-critical CO2 was the most efficient for extracting the acidic cannabinoids (suffix "A") while ethanol and isopropanol extractions were most efficient for extracting the neutral cannabinoids.

Medical Cannabis Effective for Orthopedic Pain

"Medical cannabis use was associated with clinical improvements in pain, function, and quality of life with reductions in prescription drug use; 73% either ceased or decreased opioid consumption and 31% discontinued benzodiazepines."

Study: CBG Effective for Several Conditions

This study, co-authored by Dr. Ethan Russo was published in Cannabis & Cannabinoid Research in September 2021. It explored the self-reported effectiveness in CBG dominant cannabis or hemp products.

Cannabis strain names and labels aren't consistent

Indica, Sativa, & Cultivar Names Aren't Consistent

"we determined that pairs of samples with identical cultivar names (for example, OG Kush) were often as genetically and chemically distant from each other as pairs of samples with different names" (i.e. always check the COA for individual terpenes)

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WARNING: Everyone has unique biochemistry, preexisting conditions, and mental state. Almost all medicinal and psychotropic products can cause adverse side effects in some people. The same is true with cannabinoid products, especially when they contain psychotropic cannabinoids like THC. Be very careful. Reported or statistically implied adverse effects include, but are not limited to: cannabis hyperemesis syndrome (CHS), adverse cardiovascular events (stroke, heart attack), arrhythmia, psychosis, and addiction (cannabis use disorder, or CUD).

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