Published Research Summaries (click "Search" in Menu to filter)

CBG kills pancreatic tumor cells in vitro

The most common form of pancreatic cancer is pancreatic ductal adenocarcinoma (PDAC). It has a poor prognosis primarily due to its chemotherapy resistance - less than 10% survival rate after 5 years. This study examined the effects of CBG.
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CBD shows anti-tumor effects in colorectal cancer cells

This study investigated the cytotoxic effects of CBD in a panel (in vitro) of colorectal cancer (CRC) cells. It was published in the Journal of Cellular Biochemistry in February 2024.
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Topical CBD use significantly improves gingivitis and reduces periodontal bacteria

"The clinical trial demonstrated a statistically significant improvement after CBD application." It was published in the Journal of Periodontal Research in February 2024.
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How cannabis extract kills melanoma cells

Building on previous work that demonstrated that a full-spectrum CBD extract helped kill melanoma cancer cells, this study was focused on identifying the mechanisms involved in how cell death was triggered. It was published in the journal Cells in January 2024.
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Cannabis helps UK patients with treatment-resistant insomnia

Some experts estimate sleep disturbances could affect 33% of the population, while about 10% of adults actually meet the criteria for full-fledged insomnia disorder. This study examined sleep‐specific health‐related quality of life for those prescribed cannabis‐based medicinal products for insomnia.
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CBD flower beats THC flower for anxiety reduction

Over 4 weeks, participants' changes in anxiety symptoms were measured using the Patient Global Impression of Change scale and the Depression, Anxiety, and Stress Scale. They also measured changes in the patients' perception of their mood changes after taking cannabis using several subscales of the Profile of Mood States.
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German patients say medical cannabis is effective

Germany made cannabinoid medicine available by prescription in 2017. This study wanted to learn more about how these patients feel about its effectiveness. It was published in the journal Frontiers in Medicine in December 2023.

 

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CBD isolate improves treatment-resistant infantile epileptic spasms syndrome

This study tested high dose CBD isolate as an add on treatment for infants diagnosed with infantile epileptic spasms syndrome who did not respond to traditional treatments. It was published in January 2024 in the journal Seizure, the European Journal of Epilepsy.
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Diagnosed depression patients report good results with cannabinoid medicine

This study examined the effectiveness of cannabis medicine on patients diagnosed with Major Depressive Disorder. It was published online ahead of print in January 2024 the journal Pharmacopsychiatry.
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Cannabis for neuropathic pain among Spinal Cord Injury patients

This type of pain is severe and highly treatment-resistant, so ANY improvement in pain scores is helpful. Traditional pharmaceutical approaches have not been shown to be consistently effective.
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Cannabis use corresponds with improved anxiety, sleep quality, and quality of life for ADHD patients

This study examined the effect of cannabis-based medicinal products on key measures of health-related quality of life in patients diagnosed with attention-deficit hyperactivity disorder (ADHD). It was published in December 2023 in the journal Neuropsychopharmacology Reports.
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Does medical cannabis really cause cognitive impairment?

They used the Cambridge Neuropsychological Test Automated Battery (CANTAB) and Druid application to determine levels and changes in cognitive function before and after patients self-administered their standard dose of medical cannabis.
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High doses of CBD do not help reduce osteoarthritis pain when used with paracetamol

This was a randomized, double-blind, placebo-controlled clinical trial investigating the effectiveness of 600mg of CBD to reduce osteoarthritis knee pain when used in conjunction with paracetamol. It was published in The Lancet Regional Health - Europe in December 2023.
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Joint smoking study: The second half is always "stronger"

The transition of cannabinoids and terpenes in cannabis from "solid" to vapor or smoke in a joint (cannabis cigarette) was examined. It was published in the journal Cannabis and Cannabinoid Research in October 2023.
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Cannabis helps anxiety patients get better sleep

Participants self-reported their sleep quality, alcohol use, and cannabis use daily for 30 days via a dairy. It was published in November 2023 in the Drug and Alcohol Review from the Australasian Professional Society on Alcohol and other Drugs.
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Male cannabis users have lower kidney stone risk, female users do not

Using data from the U.S. National Health and Nutrition Examination Survey (NHANES) from 2009 to 2018, this study sought to determine if there was an association between marijuana use and kidney stones.
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Cannabis improves pain symptoms in non-responsive cancer patients

Many cancer patients do not respond to traditional pharmaceutical pain interventions. This study examined the self-reported effectiveness of medical cannabis on pain in non-responsive cancer patients.
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Study concludes cannabis users do not show increased heart disease risk factors

Published in November 2023 in the journal Circulation: Cardiovascular Quality and Outcomes, this study examined data collected by the US National Health And Nutrition Examination Survey from 2005 to 2018.
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