CBD isolate helps with menstrual-related symptoms

This open-label study (patients knew which product they were taking) was designed to determine if CBD isolate was effective at alleviating menstrual-related symptoms (MRS). It was published in the journal Experimental and Clinical Psychopharmacology in March 2024.

It included 23 women who took specific doses of CBD isolate via softgel capsules for 5 days when their symptoms started. They took either 160mg CBD twice a day or 320mg CBD twice a day for 5 consecutive days starting on the first day of symptom recognition. They did this for 3 consecutive months.  All women also completed a 1 month baseline without CBD before starting CBD use.



reductions (in both dosing groups) in MRS, irritability, anxiety, global impression of change, stress, and subjective severity scores when comparing baseline to all 3 months of CBD consumption. 

changes in symptoms appeared in the first month of CBD consumption and persisted over the 3 consumption months


Authors' conclusions:

Findings suggest that CBD may have the potential for managing MRS.


The article abstract is available here at PubMed.



Ferretti ML, Stanley TB, Peters EN, Bonn-Miller MO, Irons JG. Examination of the effects of cannabidiol on menstrual-related symptoms. Exp Clin Psychopharmacol. 2024 Mar 7. doi: 10.1037/pha0000709. Epub ahead of print. PMID: 38451730.