Published Research Summaries (click "Search" in Menu to filter)

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Cannabis & chronic neuropathic pain (review study)

Eight randomized controlled trials were included in the analysis. Six showed significant improvement in sleep quality and eight showed a significant reduction in pain scores.
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Chronic pain and cannabis: helps reduce other pain medications

This study collected and analyzed patient information on their use of cannabis for chronic non-cancer pain. The research letter was published in January 2023 on the Journal of the American Medical Association (JAMA) Network.
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Cannabis use does not predispose users to high blood pressure

This study retrospectively evaluated data collected by the National (US) Health and Nutrition Examination Survey from 2017 to 2018. It examined the relationship between past cannabis use and hypertension (high blood pressure). It was published in December 2022 in The Journal of Clinical Hypertension.
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New study reinforces positive results for cannabis use and Multiple Sclerosis

Published in the International Journal of MS Care in December 2022, this study examined medical cannabis (MC) as part of a comprehensive treatment plan for patients with Multiple Sclerosis (MS).
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CBD isolate helps patients with Treatment Resistant Epilepsy

This study was published in December 2022 in the journal Epilepsia. It examined CBD isolate as an add-on treatment in patients suffering from treatment resistant epilespy (TRE). For the patients that completed the study, their seizures were reduced by about one-half to two-thirds over a period of almost 2 years.

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Study: Cannabis helps some with headaches

The data was collected from 200 patients in a tertiary headache clinic in Alberta, Canada. They tracked the headache diagnosis and frequency, the doses and methods of cannabinoid delivery, patient benefits, and adverse effects.
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Cannabinoids and Terpenes tested for their effects on inflammation

The results showed that the cannabinoids worked much better than terpenes, and that THC showed the greatest immune modulating activity of all molecules tested. CBDV and CBG followed THC, while CBD ranked last in their experiments.
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THC and CBD seem to help heal wounds and slow skin aging

This study examined the effects of THC and CBD on human skin models to determine if they could assist in wound healing, and slow the process of skin cell aging. It was published in December 2022 in the journal Cells.
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THC recommended as a cardioprotective drug for some conditions

This research was conducted to determine if THC might have protective effects in the treatment of cardiovascular system dysfunction arising from Ischemia / Reperfusion (IR). IR is loss of blood flow, then the return of blood flow to the heart - both conditions can create damage or injury.
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Full spectrum cannabis extract shown to kill Ovarian Cancer cells

This in vitro (in a lab) study examined the effects of different cannabinoid combinations of ovarian cancer cell models. It was published in the journal Molecules in October 2022. One mixture was 50 times more cytotoxic to cancer cells than to normal cells.

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man sitting on a beach contemplating why cannabis doesn't help his pain

Study: Your genes can affect how well cannabis works for chronic pain

This study followed 600 chronic pain patients for 12 months to determine if there was any correlation between their genetic differences and the effectiveness of cannabis medicine treatment. It was published in the journal Genes in October 2022.
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Cannabinoids work for treatment resistant chronic pain, but not for everybody

Treatment refractory chronic pain (TRCP) is chronic pain that is resistant to conventional analgesics (pain killers) or creates intolerable adverse events (AEs) from those. This study examined the effectiveness of oral cannabinoids on this condition and was published in November 2022 in the European Journal of Pain.
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Some children with autism (ASD) respond well to full spectrum CBD extract

This study followed 82 children and adolescents with autism spectrum disorder (ASD) for 6 months to determine the effects of CBD oil. It was published in Translational Psychiatry in September 2022.

 

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Cannabis improves dementia symptoms (Sept 2022 controlled trial)

Conclusion: In this randomized controlled trial, ‘Avidekel’ oil significantly reduced agitation over placebo in patients suffering from behavioral disturbances related to dementia, with non-serious side-effects.
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Does cannabis use impact healing after spinal fusion surgery?

This study analyzed the effects of cannabis use on healing after Thoracolumbar Spinal Fusion (TLF) surgery, where screws and rods are implanted to steady the spine. In short, cannabis users had about one half the complication rates after 90 days than did non-users.

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Adolescent cannabis use and psychosis

They found that diagnosed adult psychosis was "likely attributable to familial confounds rather than a causal effect of cannabis exposure." That is pretty clear. Here is a quick summary of how they came to that conclusion.
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Cannabis helps women with treatment-resistant Fibromyalgia (November 2022)

The study followed 30 women ages 18-70 who suffered from fibromyalgia and had experienced no improvement through traditional pharmacological treatment.
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Oral cannabis consistently improves health outcomes over two years

This study followed 3,961 patients with multiple condictions for two years to determine the effects of regular, consistent doses of oral cannabis medicines. It was published in the journal PLOS One in November 2022.
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