Flavonoids (14)

Flavonoids are another "class" of active ingredients in The Amazing Flower, along with Cannabinoids and Terpenes. Like Terpenes (and Terpenoids), Flavonoids are active ingredients that many believe have a profound impact on the effect of cannabis and hemp products. They are not usually tested for, but they are starting to show up in some COAs (Certificates of Analysis) of flower. Most of the Flavonoids in cannabis and hemp are found in other plants - mostly fruits, vegetables, and flowers, but there are a few that are unique to cannabis and hemp. One cannabis Flavonoid was recently shown to increase the survival rate of animals with pancreatic cancer.

Our goal is to always try to simplify and summarize known information, or common knowledge, so everyone has easy access to the best knowledge available about active ingredients. It's estimated that Flavonoids could make up 2-3% of cannabis and hemp flower's dry weight. It seems the main purpose of Flavonoids is to give color to plants, especially their flowers, to help attract pollinators and filter light. They are responsible for the yellow, red, blue, and purple colors in plants, including cannabis and hemp.

The most commonly found flavonoids in cannabis & hemp are the anthoxanthins listed below that contribute mostly a yellow coloration. But another class, the anthocyanins, are also found in some cultivars, and they contribute to any red, purple, & blue coloration. Anthocyanins are highly volatile and vary depending on the pH level and temperature. Acidic environments usually produce a red or pink color. A neutral pH level usually produces purple color, and alkaline environments produce a bluish color.

There are a lot of outstanding, detailed, and much more scientific articles and blog posts about the flavonoids in cannabis, and we encourage everyone to learn as much as they can. What we present here is meant to be a quick-reference summary of the most important knowledge for patients and consumers - knowledge that they can access quickly and easily, any time they need or want it.

Below are 14 of the major Flavonoids frequently found in cannabis and hemp, along with their general properties and characteristics. We have, in good faith, curated the best information from multiple sources, but research is very limited and there are some disagreements. Use this as a starting point for your own exploration. If you see an error or omission, please let us know!

Please note the very high boiling point of most of these flavonoids. That means you probably aren't going to get them into your bloodstream unless you tincture or ingest them. Smoking and vaporizing will not usually reach the temperatures needed to vaporize most of these flavonoids, but there are 5 exceptions. As with our Terpene List, those in blue text are considered to have some sedative effects.

 

Apigenin
Also found in parsley, onions, and oranges.
Boiling Point: 352ºF
Reported Benefits: anti-anxiety, anti-inflammatory, anti-tumor, neurological relief or protectant, sedative

Cannflavin A
Only found in cannabis and hemp.
Boiling Point: 360ºF

Primary Color Contribution: Yellow
Reported Benefits: analgesic (pain reduction), anti-inflammatory, antimicrobial, anti-tumor, neurological relief or protectant

Cannflavin B
Only found in cannabis and hemp.
Boiling Point: 1126ºF

Primary Color Contribution: Yellow
Reported Benefits: analgesic (pain reduction), anti-inflammatory, antimicrobial, anti-tumor, neurological relief or protectant

Cannflavin C
Only found in cannabis and hemp.
Boiling Point: 360ºF

Primary Color Contribution: Yellow

Reported Benefits: analgesic (pain reduction), anti-inflammatory, antimicrobial, anti-tumor, neurological relief or protectant

Catechin
Also found in camomile, black grapes, and tea leaves.
Boiling Point: 1167ºF

Primary Color Contribution: Yellow

Reported Benefits: anti-inflammatory, anti-tumor, hypertension relief or aid

Isovitexin
Also found in cocoa, passion flower, and bamboo.
Boiling Point: 1465ºF

Primary Color Contribution: Yellow

Reported Benefits: anti-inflammatory, anti-tumor, neurological relief or protectant

Kaempferol
Also found in apples, broccoli, and grapefruit.
Boiling Point: 658ºF

Primary Color Contribution: Yellow

Reported Benefits: antidepressant, antidiabetic, anti-inflammatory, antimicrobial, anti-tumor

Luteolin
Also found in celery, pepper, and thyme.
Boiling Point: 1141ºF
Primary Color Contribution: Yellow

Reported Benefits: anti-inflammatory, antimicrobial, anti-tumor, hypertension relief or aid

Orientin
Also found in acai palm, bamboo leaves, and Indian basil.
Boiling Point: 1501ºF

Primary Color Contribution: Yellow

Reported Benefits: analgesic (pain reduction), antidepressant, anti-inflammatory, antimicrobial, anti-tumor, neurological relief or protectant

Quercitin
Also found in onions, apples, grapes, berries, broccoli, citrus fruits, & many other fruits and vegetables.
Boiling Point: 482ºF
Primary Color Contribution: Yellow

Reported Benefits: analgesic (pain reduction), anti-inflammatory, antimicrobial, anti-tumor, neurological relief or protectant

Rutin
Also found in buckwheat, citrus peels, and the pagoda-tree.
Boiling Point: 1802ºF
Primary Color Contribution: Yellow

Reported Benefits: analgesic (pain reduction), anti-inflammatory, anti-microbial, hypertension relief, anti-tumor

Silymarin
Also found in milk thistle, holy thistle, and variegated artichoke.
Boiling Point: 1460ºF

Primary Color Contribution: Yellow
Reported Benefits:
anti-inflammatory, antimicrobial, anti-tumor

Sitosterol (beta-Sitosterol)
Also found in peanuts, wheat germ, and rice bran.
Boiling Point: 273ºF
Reported Benefits: anti-inflammatory, hypertension relief

Vitexin
Also found in hawthorne, wheat germ, and rice bran.
Boiling Point: 1413ºF

Primary Color Contribution: Yellow

Reported Benefits: analgesic (pain reduction), anti-inflammatory, anti-tumor, neurological relief or protectant