This study on rats will be published in the journal Experimental Neurology in December 2021. It examined the effects of CBD applied directly to the site of a traumatic brain injury (TBI), as well as CBD injected systematically to the blood stream.
The study concluded that the local (at the injury site) CBD implant combined with a systematic injection of CBD through standard injection (CBDi+IP) worked best when compared to either method by itself. The following quote explains their very encouraging conclusions.
"Post-injury administration of CBDi+IP greatly reduced defecation scores, lesion volume, the loss of neurons in the ipsilateral hippocampus, the number of injured neurons of the contralateral hippocampus, and reversed TBI-induced glial fibrillary acidic protein (GFAP) upregulation which was superior to either CBD.IP or CBDi treatment alone."
The abstract of the paper is here.