This was a single-site randomized controlled trial published in the journal Neuropsychopharmacology in July 2021. It used blood samples to determine if CBD helped reduce inflammation markers in Cocaine Use Disorder (CUD) patients.
The participants received 800mg CBD per day or placebo for 92 days. As with MANY serious conditions, the dose of CBD is high, especially for the adult-use market. But the side effects are still usually minor, even for these dosage levels.
"Participants treated with CBD had lower levels of interleukin-6, vascular endothelial growth factor, intermediate monocytes, and natural killer CD56negCD16hi compared with participants receiving placebo."
So yes, it does seem that CBD can help reduce inflammation in this case.
The abstract is here.