Published in the Journal of Clinical Psychopharmacology in August 2021, this naturalistic, randomized, double-blind, crossover, placebo-controlled study explored the differences in the psychotomimetric effects (euphoric effects, or the "high") of THC vs. CBD vs. THC+CBD together.
The study tested 18 cannabis-experienced members of a cannabis social club and asked them to report the psychotomimetic effects using different types of extracts: 1) THC only, 2) CBD Only, 3) THC+CBD combined, or 4) placebo. The results showed that the euphoric effects of THC only were higher than when THC+CBD was used. CBD only did not have any euphoric effects.
It is almost considered common knowledge in the industry these days, but here is more evidence to support the reality that adding CBD can help manage the negative side effects of THC for some people.
"Ultimately, this study substantiates the link between the endocannabinoid system and psychotic-like symptoms and has important implications for the understanding of schizophrenia and the therapeutic potential of CBD as an antipsychotic."
The study abstract is here at Europe PMC.