Bisabolol and Caryophyllene show neuroprotective qualities

These two common cannabis terpenes were shown to have neuroprotective qualities in vitro (test tube in a lab). The research paper appears in the journal NeuroToxicology in May 2022.

The study tested α-bisabolol, β-caryophyllene, and myrcene and their effects on standard neurological cell models. The study showed that Bisabolol and Caryophyllene had positive and neurogenerative effects on these cells with Bisabolol having the greatest effect. They found that Myrcene did not have an effect.

"α-bisabolol also demonstrated a significant neuroprotective effect against amyloid β exposure, with β-caryophyllene also providing a lesser, but significant increase in cell viability."

"This demonstrates that bioactivity of selected terpenes should be a consideration in the emergent use of medicinal cannabis formulations for the treatment of neurodegenerative diseases."

The research abstract is here at ScienceDirect.com.